Hitomi starts as one of the protagonists of the Killing Bites manga, becoming a potential antagonist and rival of her co-protagonist (Nomoto Yuuya) later on. After a rather fateful meeting with Nomoto, she becomes a temporary ally with the Ishida Zaibatsu, one of the four major business conglomerates which handle all the affairs in regards to the hybrids. She's an integral part of Shidou Reiichi's mysterious agenda.